G is for Grierson Gopalan Syndrome

December 4, 2021

Grierson Gopalan Syndrome was originally described by Grierson in 1829 and Gopalan in 1946 and is a term that is now used as a synonym for burning feet.

Burning feet, also known as neuropathy or paresthesia, refers to a sensation of heat, tingling, or burning in the feet. It can occur in one or both feet and may vary in intensity.

Burning feet can be caused by various factors, including:

  1. Peripheral neuropathy: This condition involves damage to the peripheral nerves, which can result from diabetes, alcohol abuse, certain medications, vitamin deficiencies, autoimmune diseases, and other underlying medical conditions.
  2. Nerve compression: When nerves in the feet become compressed or entrapped, such as with Morton’s neuroma or tarsal tunnel syndrome, it can cause burning sensations.
  3. Nerve damage: Injury or trauma to the nerves in the feet, such as from accidents, surgeries, or repetitive stress, can lead to burning sensations.
  4. Circulatory problems: Reduced blood flow to the feet due to conditions like peripheral artery disease (PAD) or Raynaud’s disease can result in burning sensations.
  5. Infections: Certain infections, including athlete’s foot (fungal infection) or peripheral neuropathy caused by HIV or Lyme disease, can cause burning feet.
  6. Certain medications and toxins: Some medications, such as chemotherapy drugs, can cause peripheral neuropathy and burning feet as a side effect. Exposure to certain toxins, like heavy metals, can also lead to nerve damage and associated symptoms.
  7. Other causes: Other possible causes include vitamin deficiencies (such as vitamin B12 deficiency), thyroid disorders, kidney disease, alcoholism, and certain inherited conditions.


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